FISH Keeps Swimming in Vast Waters

The FISH trial, a randomized controlled trial (RCT) comparing the effectiveness of surgical and nonsurgical treatments for humeral shaft fractures, has reached another milestone. The 1- and 2-year results were previously published in JAMA and JAMA Surgery, respectively. With the news embargo now lifted, we are delighted to announce that the FISH trial continues to navigate the same waters, presenting its 5-year results in the prestigious JAMA.

The key takeaway: The 32% of patients from the functional bracing group who underwent secondary surgery, and initially exhibited inferior results at the 1- and 2-year follow-ups, no longer demonstrate clinically relevant differences at the 5-year mark.

This achievement fills us with joy, and we extend our sincere gratitude to every member of the FISH investigators for their tremendous efforts!

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